SYSTEMS AND METHODS FOR ANALYZING GENE EXPRESSION

专利名称：SYSTEMS AND METHODS FOR ANALYZING

GENE EXPRESSION DATA FOR CLINICALDIAGNOSTICS

发明人：ANDERSON, Glenda, G.,MORALEDA, Jorge申请号：EP04821586.7申请日：20040929公开号：EP1690086A2公开日：20060816

摘要：Methods, computer program products and computer systems for constructinga classifier for classifying a specimen into a class are provided. The classifiers are models.Each model includes a plurality of tests. Each test specifies a mathematical relationship(e.g., a ratio) between the characteristics of specific cellular constituents. Each test ispolled using characteristic values of these specified cellular constituents from thebiological specimen to be classified. In some embodiments, each test has a positivethreshold and a negative threshold. When the value of the test exceeds the positivethreshold, the test polls positive. When the value of the test is below the negativethreshold, the test polls negative. When the value of the test is between the negativethreshold and the positive threshold, the test polls indeterminate. The value of each testis combined to provide a composite score. In some embodiments, positive compositescores indicate that the specimen belongs in the class associated with the model.

申请人：Pathwork Informatics, Inc.

地址：2 Noth First Street, Second Floor San Jose, CA 95113 US

国籍：US

代理机构：Jones Day

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