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脑白质疏松与脑出血

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脑白质疏松与脑出血

王建

徐文安

    [摘要]脑白质疏松(leukoaiois,LA)合并卒中较为常见。研究显示,LA与脑出血的发生和预后密切相关。文章对LA与原发性脑出血、抗凝和溶栓治疗后脑出血以及脑微出血的关系进行了综述。

脑白质疏松症;脑出血;脑淀粉样血管病;抗凝药;血栓溶解疗法

Leukoaraiosis and intracerebrai hemorrhage

WANG JianXU Wen-an

Department of Neurology, the Fourth Clinic College of Anhui Medicd University, the Second 

People's Hospitd of Hefei, Hefei 230011, China

      [ Abstract]  Leukoaraiosis (LA) complicating stroke is more common. Studies have shown 

that LA is closely associated with the occurrence and prognosis of intracerebral hemorrhage. This article reviews the relationship between LA and primary intracerebral hemorrhage, intracerebral 

hemorrhage after anticoagulant and thrombolytic therapies as well as cerebral microbleeds.

Leukoaraiosis; Cerebral hemorrhage; Cerebral amyloid angiopathy; Anticoagulants; Thrombolytic therapy

103760/cma.j.issn.1673 -4165.2011.09.010

    作者单位:230011合肥,安徽医科大学第四临床学院,合肥市第

二人民医院神经内科

万方数据万方数据・695・

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       Group. Leukoaraiosis is a risk factor for symptomatic intracerebral             h e m2or4r6ha3g-e2 a4f6t6er.

 thrombolysis for acute stroke. Stroke, 2006, 37: 

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@ @ [ 1 0乡医学院学报,]  李卉,吴永明,2姬仲,008, 等.25脑出血伴脑白质疏松症7:165-168.

6例分析.新

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        and Disability in the Elderly) Study. Cerebrovasc Dis, 2006, 21: 315-322.

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               p eo p1le0:4 .

MR-pathologic correlations. Magn Reson Med Sci, 2006, 5: 99-

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              b o ly4s8is4--r4el9a2t.

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 in acute intracerebral hemonrrhage. Stroke, 2007, 38:

        Group. Importance of leukoaraiosis on CT for tissue plasminogen 

         activator decision making: evaluation of the NINDS rt-PA Stroke 

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         Study. Cerebrovasc Dis, 2008, 26: 120-125.

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        2006, 67: 83-87.

        tions, and potential clinical implications. Neurology, 2006, 66: 165-

@ @ [  1 7  ]     InSztitraorki eD,.  L2e0uk0o3a,ra i3os4i:s : 2a0n6 i7n-d2ep0e7nd1e.nt risk factor for stroke?

         171.

@@[24]  Tsushima Y, Aoki J, Endo K. Brain microhernorrhages detected on @@[ 18 ]  Arsava EM, Rarnan R, Rosand J, et al. Severity of leukoaraiosis                T2  2*0 0-w3e,i gh2t4e:d  g8r8a-di9e6n.

t-echo MR images. AJNR Am J Neuroradiol, 

        correlates with clinical outcome after ischemic stroke. Neurology,        2009, 72: 1403-1410.

@@[ 25 ]  Liu PF, Cui YZ, Na J, et al. Cerebral rmicrobleeds— prevalence, distribu@@[ 19]  Gretkes C, Nowak DA, Eickhoff SB, et al. Cortical connectivity after         tion and risk factors in northeast population without preceding large-area 

        subcortical stroke assessed with functional nagnetic resonance imaging 

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@ @ [  2 0]     Fl ahNeertuyr MoLl. ,A nt2i0co1a0gu,l a3nt0-a:s so5c6i5at-ed5 7in2t.

racerebral hemorrhage. Semin 

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        2002, 59: 425-429.

        ischemia: patterns and risk factors. Stroke Prevention In Reversible 

2011-04-13

2011-05-06

脑动

万方数据脑白质疏松与脑出血

作者:作者单位:刊名:英文刊名:年,卷(期):

王建, 徐文安, WANG Jian, XU Wen-an

230011合肥,安徽医科大学第四临床学院,合肥市第二人民医院神经内科国际脑血管病杂志

International Journal of Cerebrovascular Diseases2011,19(9)

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