METHOD AND DEVICE FOR ANALYSING MOLECULAR INTERACT

专利名称：METHOD AND DEVICE FOR ANALYSING

MOLECULAR INTERACTIONS, AND USESTHEREOF

发明人：TURKCAN, SILVAN,ALLAIN, JEAN-MARC,ALEXANDROU, ANTIGONI

申请号：EP11752276.3申请日：20110721公开号：EP2596351B1公开日：20140625

摘要：The invention relates to a method for analysing an interaction between a firstmolecule and a second molecule bonded to a particle, including the following steps:contacting the first molecule with the second molecule bonded to the particle underconditions enabling the interaction thereof; applying a predetermined liquid flow to theparticle bonded to the second molecule; observing a movement of the particle bondedto the second molecule caused by the applied flow; analysing the interaction accordingto the movement observed and the applied flow, the particle having a greaterhydrodynamic resistance than the first and/or second molecule, and a mass Pécletnumber of greater than 1. The invention also relates to a device for analysing aninteraction between a first molecule and at least one second molecule, as well as to theuse of the method or of the device in screening a candidate molecule for developing adrug.

申请人：ECOLE POLYTECHNIQUE / DGAR,ECOLE POLYTECHNIQUE DGAR,ECOLEPOLYTECHNIQUE / DGAR

地址：FR

国籍：FR

代理机构：Novagraaf Technologies

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