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Process for the preparation of 2-amino-ethanesulfo

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专利名称:Process for the preparation of 2-amino-ethanesulfonylazide acid addition slats, 2-amino-ethanesulfonylazide hydrochloride aswell as its use

发明人:HERDEIS, CLAUS,WEIS, CHRISTIAN EDWIN申请号:EP98103843.3申请日:19980304公开号:EP0863133A2公开日:19980909

摘要:Preparation of 2-aminoethanesulphonylazidic acid addition salts comprises: (a)oxidative halogenation of 2-aminoethanethiol or bis-(2-aminoethyl)-disulphide, both inacid addition salt form, to give 2-aminoethanesulphonyl halogenide acid addition salt; and(b) reacting the acid addition salt with the corresponding nucleophilic azide in a polarsolvent. Also claimed are: (A) 2-aminoethanesulphonylazide hydrochloride; and (B) theuse of 2-aminoethanesulphonylazide hydrochloride (which does not need to beseparated from the solution produced in step b)) for the preparation of 2-aminoethanesulphonylamide hydrochloride, which is then reacted with formaldehyde togive taurolidine or taurultam.

申请人:HERDEIS, CLAUS,WEIS, CHRISTIAN EDWIN

地址:Strassbergerstrasse 18 80809 München DE,Jägerstrasse 5a 97297Waldbüttelbrunn DE

国籍:DE,DE

代理机构:Andrae, Steffen, Dr.

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